The organ on a chip will enable more innovative and flexible systems for mimic tissues, organ, human and other organisms. The organ-on-a-chip is categorized on the basis of an organ such as lung-on-chip, heart-on-chip, kidney-on-chip, and others such as artery-on-chip and skin-on-chip. There are various applications addressed by this technology such as drug discovery and toxicology research. In addition, it finds its application in the cosmetic industry. The major driver for this market is the development of human tissue chips for improvement in drug discovery and improvement in the prediction of organ toxicity liabilities.